TB Research

Case Series of Primary Esophageal Tuberculosis.

Hong-Mei Chen, Sha-Na Zhang, Jing Tong, Chen-Guang Li, Meng-Qiu Gao, Qiang Li

The American journal of tropical medicine and hygiene · 2026-04

Abstract

Gastrointestinal tuberculosis is a relatively common form of extrapulmonary tuberculosis. Primary esophageal tuberculosis is rare and frequently misdiagnosed or delayed in diagnosis by clinicians. Four cases of primary esophageal tuberculosis are reported. All patients involved underwent pathological examination of their esophageal lesions, which revealed granulomas. Additionally, molecular detection confirmed the presence of Mycobacterium tuberculosis DNA in two cases. All patients received antituberculosis therapy and achieved good outcomes.