Landscape of metagenomics: fight against tuberculosis and other infectious disease in India.

Metagenomics is an evolving diagnostic tool worldwide for studying microorganisms which cannot be cultured in routine laboratory settings. From Sanger sequencing to Next Generation Sequencing like Illumina, and now Oxford Nanopore sequencing has been a boon in detecting difficult-to-diagnose infectious disease conditions and delivering patient-tailored treatment. In developing countries like India, these advancements in diagnostics aid in decreasing disease burden, growing antimicrobial resistance and to study new microorganism.