TB Research

Challenges in the Diagnosis and Treatment of Mycobacterium abscessus Infections.

Ana Júlia Reis, Michael Andrés Abril Gómez, Mariana Quaresma de Souza, Júlia Silveira Vianna, Ivy Bastos Ramis, Pedro Eduardo Almeida da Silva

Revista da Sociedade Brasileira de Medicina Tropical · 2026-01

Abstract

The Mycobacterium abscessus complex (MABC) includes non-tuberculous mycobacteria that are widely distributed and clinically significant. Similar to tuberculosis, MABC can lead to skin and soft tissue infections and pulmonary diseases. These infections frequently occur in outbreaks, particularly among immunocompromised patients or those with preexisting pulmonary conditions. This review examines the recent progress in essential areas that define these infections as a significant challenge in medical practice, specifically the diagnostic modalities, antibiotic treatment options, and resistance of MABC to antibiotics and biocides.

MeSH terms

  • Humans
  • Mycobacterium Infections, Nontuberculous
  • Mycobacterium abscessus
  • Anti-Bacterial Agents