Molecular Identification of Mycobacterium bovis in Human Pulmonary Tuberculosis: Insights from a Tertiary Care Hospital in Gujarat, India

BACKGROUND: in cases of pulmonary tuberculosis in a tertiary care teaching hospital located in Karamsad, Anand, a rural district of Gujarat. METHODS: Conclusion: The study found the prevalence of M. bovis in 10% cases of pulmonary tuberculosis in the Anand district of Gujarat. The findings highlight the limitations of conventional diagnostic methods in identifying M. bovis infections and demonstrate the efficacy of molecular techniques, explicitly targeting the HupB gene, for accurate detection and differentiation of M. tuberculosis and M. bovis. The evidence of coinfection in 6% patients further emphasizes the complexity of tuberculosis diagnosis in endemic areas.