TB Research

Tuberculosis diagnosis using artificial intelligence: current trends and future prospects

O. Mbulayi, Saint-Jean Djungu, Loukia Aketi, Mohammed Amine Koulali, Hanae Azzaoui, Rim Koulali, Mohammed El Mzibri, Imane Chaoui, et al. (9 authors)

Frontiers in Medicine · 2026-01

Abstract

, poses a major global health challenge. Despite being largely controlled for several decades, tuberculosis has experienced a resurgence in recent years. China has the second highest incidence of tuberculosis globally, with a prevalence of 459 cases per 100,000 individuals aged 15 years old. Chest radiography and pathology are essential tools for its detection and diagnosis. However, the small size and low number of tubercle bacilli make detection and identification under a microscope challenging, often resulting in low detection rates and false diagnoses. Artificial intelligence (AI) has emerged as a promising tool to improve the accuracy and sensitivity of tuberculosis detection. This review provides a comprehensive overview of the literature on the use of machine learning-based models for the automatic detection of tuberculosis bacilli, emphasizing the advantages of integrating in tuberculosis diagnosis. Understanding the onset and progression of tuberculosis is crucial to developing effective strategies for its diagnosis, treatment, and prevention.

MeSH terms

  • Tuberculosis
  • Medicine
  • Intensive care medicine
  • Disease
  • Tuberculosis diagnosis
  • Mycobacterium tuberculosis
  • Incidence (geometry)
  • Global health
  • Identification (biology)
  • Tuberculosis control
  • Infectious disease (medical specialty)
  • Case finding