TB Research

The development of an adherence to treatment scale for pulmonary TB.

Y A Prasetyo, S Thanasilp, S Preechawong

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2025-08

Abstract

<sec><title>BACKGROUND</title>Effective TB treatment requires consistent adherence, yet traditional assessments focus solely on medication intake and may miss important lifestyle factors. This study aimed to develop and evaluate the psychometric properties of the Adherence to TB Treatment Scale (ATTS), a new instrument covering both medication intake and lifestyle behaviours.</sec><sec><title>METHOD</title>The development followed seven steps: 1) defining TB treatment adherence through literature synthesis and a Delphi study, 2) generating an item pool from an extensive literature review, 3) using a four-point Likert scale for measurement, 4) assessing item validity, 5) conducting preliminary studies, 6) performing factor analysis, and 7) finalising the scale. Seven components were identified: medication-taking behaviour, nutritional care, substance use cessation, stress management, physical activity, sleep quality, and preventive behaviours.</sec><sec><title>RESULTS</title>The ATTS showed strong content validity (content validity index = 0.92) and reliability (Cronbach's alpha = 0.894). Exploratory factor analysis identified 33 items across seven domains. Confirmatory factor analysis indicated a good model fit: &#x3c7;&#xb2;/df = 1.97, comparative fit index = 0.94, Tucker-Lewis index = 0.88, root mean square error of approximation = 0.066, and standardised root mean square residual = 0.054.</sec><sec><title>CONCLUSION</title>The ATTS is a reliable and valid tool for assessing TB treatment adherence, including both medication and lifestyle factors, with applications in clinical practice, nursing education, and research.</sec>.

MeSH terms

  • Tuberculosis, Pulmonary
  • Antitubercular Agents
  • Psychometrics
  • Medication Adherence
  • Patient Compliance
  • Exercise
  • Sleep
  • Healthy Lifestyle
  • Indonesia
  • Humans
  • Male
  • Female
  • Adolescent
  • Young Adult
  • Adult
  • Middle Aged
  • Delphi Technique
  • Drug Monitoring