Tuberculosis in Transplant Setting - Implications in Diagnosis, Treatment and Prevention.

India is a high endemic country for tuberculosis. The prevalence of tuberculosis rises in patients undergoing solid organ transplant with a high morbidity and mortality. Immunosuppressive drugs used after liver transplant have significant interactions with ATT necessitating changes in approach to treatment of tuberculosis. Also being a high endemic zone for TB, role of preventive therapy for latent TB becomes questionable in India. We hereby discuss the diagnostic strategy, change in drug treatment & role of latent TB in patients undergoing liver transplant in India.