Smartphone-assisted tuberculosis detection by a smart amplification process and lateral flow immunoassay with a 3D-printed device.
Chung-An Chen, Natalie Yi-Ju Ho, Chang-Chi Yang, Hui-Yi Hsiao, Tse-Hao Huang, Ming-Kai Hsieh, Po-Liang Lai, Tsung-Ting Tsai
Chemical communications (Cambridge, England) · 2025-08
Abstract
A portably 3D-printed sensing platform combining a sunrise-biotin-labeled smart amplification process (sb-SmartAmp) and stacking pad lateral flow immunoassay (sLFIA) enables smartphone-assisted image analysis or naked-eye detection for on-site TB diagnosis, validated with clinical TB samples beyondtesting.
MeSH terms
- Smartphone
- Immunoassay
- Printing, Three-Dimensional
- Humans
- Tuberculosis
- Mycobacterium tuberculosis
- Biotin