TB Research

Allergic Bronchopulmonary Aspergillosis in Pediatric Asthma : A Diagnostic Challenge Mimicking Tuberculosis

Praveen Das, Santosh Kondekar, Surbhi Rathi

Digital Journal of Clinical Medicine · 2025-01

Abstract

Allergic bronchopulmonary aspergillosis (ABPA) is a rare hypersensitivity reaction to Aspergillus fumigatus, more commonly observed in adults and patients with cystic fibrosis. It can, however, present in pediatric asthmatics with refractory symptoms, leading to diagnostic challenges due to overlapping features with other pulmonary diseases, including tuberculosis. ABPA should be considered in children with uncontrolled asthma and atypical radiologic features, especially when unresponsive to standard therapies. Early recognition and appropriate management are critical to prevent irreversible lung damage and improve quality of life.

MeSH terms

  • Allergic bronchopulmonary aspergillosis
  • Medicine
  • Aspergillosis
  • Asthma
  • Tuberculosis
  • Intensive care medicine
  • Immunology
  • Dermatology
  • Refractory (planetary science)
  • Pediatrics
  • Lung
  • Allergy
  • Lung disease
  • Aspergillus