TB Research

A case of isolated testicular Tuberculosis: Approach and management

Ismail Mahad Abdullahi, Ismail Ahmed Ali, Abdirahin Mohamed Abdulkadir, Rahma Abdukadir Ahmed, Abdullahi Hassan Elmi

Urology Case Reports · 2025-12

Abstract

Testicular tuberculosis is a rare form of genitourinary TB that often mimics conditions such as neoplasms or chronic epididymo-orchitis, making diagnosis challenging. We report a 60-year-old man with longstanding right testicular pain and swelling, no systemic symptoms, and a history of household TB exposure. Imaging showed a large hydrocele with suspected underlying pathology. Intraoperative findings revealed necrotic testicular tissue, prompting orchiectomy. Histopathology confirmed granulomatous inflammation with caseous necrosis consistent with TB. The patient began standard anti-tubercular therapy. This case highlights the need to consider testicular TB in chronic scrotal swelling, particularly in TB-endemic settings.

MeSH terms

  • Medicine
  • Histopathology
  • Hydrocele
  • Caseous necrosis
  • Genitourinary system
  • Testicular tumor
  • Scrotum
  • Tuberculosis
  • Pathology
  • Orchitis
  • Granulomatous inflammation
  • Scrotal Pain
  • Extrapulmonary tuberculosis
  • Medical history
  • Necrosis
  • Testicular pain
  • Histopathological examination
  • Inflammation
  • Dermatology
  • Radiology
  • Surgery