TB Research

Clinical Commentary on: Targeting Tryptophan Metabolism for Tuberculosis Biomarkers and Host-Directed Therapy

J. Ernst

The Journal of Infectious Diseases · 2025-12

Abstract

Tuberculosis is associated with enhanced tryptophan metabolism. Whether this benefits the host or the pathogen remains to be determined, but measurements of this activity in plasma may provide opportunities for nonsputum triage tests and for monitoring tuberculosis treatment responses.

MeSH terms

  • Tuberculosis
  • Medicine
  • Immunology
  • Tryptophan Metabolism
  • Pathogen
  • Mycobacterium tuberculosis
  • Tryptophan
  • Bioinformatics
  • Triage
  • Metabolism
  • Pathogenic organism
  • Kynurenine