A Rare Case of Sarcoidosis Presenting With Endobronchial Mass
G Ramachandana, Pankti Sheth, Viswesvaran Balasubramanian, Kona Lakshmi Chermisha Naidu, Ananya Reddy Aerra
Cureus · 2025-12
Abstract
We report a rare case of sarcoidosis presenting with endobronchial mass in a 34-year-old male patient who presented with progressive shortness of breath and non-productive cough for one month. It is diagnostically challenging due to its non-specific presentations, as mass lesions can mimic malignancy. In this case, CT chest initially revealed mediastinal lymphadenopathy, multiple small peripheral lung nodules and mild right sided pleural effusion. Positron emission tomography (PET) CT revealed mediastinal lymphadenopathy and bilateral subpleural nodules. Bronchoscopy revealed a polypoid mass with a broad base in segmental bronchus of the right lower lobe. Histopathological examination of biopsy revealed granulomatous inflammation with lymphoplasmacytic infiltration, with no evidence of necrosis or malignancy. The endobronchial mass was removed using electrosurgical snaring with cryoextraction. Microbiological and cytology examinations were unremarkable. The patient was diagnosed with sarcoidosis and was initiated on oral prednisolone. This case highlights the importance of considering sarcoidosis in the differential diagnosis to ensure timely and appropriate management.
MeSH terms
- Medicine
- Sarcoidosis
- Radiology
- Differential diagnosis
- Bronchoscopy
- Biopsy
- Mediastinal lymphadenopathy
- Right Main Bronchus
- Lung
- Mediastinal Diseases
- Histopathological examination
- Chest radiograph
- Mediastinal mass
- Mediastinum
- Bronchus
- Caseous necrosis
- Granuloma
- Cytology
- Flexible bronchoscopy
- Pathology