Summary/Samenvatting

Chapter One presents a literature review of studies into the cost and cost-effectiveness of Tuberculosis (TB) control prior to researching this thesis. Although the broad strategy for TB control, Directly Observed Treatment Strategy (DOTS), is well established, it identifies areas for further research. These include the assessment of the cost-effectiveness of: re-structuring health services in middle income countries to provide DOTS; new strategies for case detection; new strategies/tools to combat the growing threat of MDR-TB; and, the integration of TB/HIV services.