TB Research

Experience with Linezolid for the Treatment of Rifampin-Susceptible Tuberculosis in San Francisco

Janice K. Louie, Gustavo E. Velásquez, Allison L. Phillips, John D. Szumowski

Open Forum Infectious Diseases · 2025-11

Abstract

Linezolid is recommended for the treatment of rifampin-resistant tuberculosis (TB), but its role in rifampin-susceptible TB (RS-TB) is less understood. In 45 RS-TB patients treated with linezolid, 8 stopped due to adverse events, most commonly cytopenias. Further research is needed on linezolid efficacy, dosing, and adverse event management in RS-TB.

MeSH terms

  • Medicine
  • Linezolid
  • Adverse effect
  • Tuberculosis
  • Intensive care medicine
  • Surgery
  • Internal medicine
  • Antibacterial agent