TB Research

Bilateral Chronic Cavitary Pulmonary Aspergillosis in a Patient With Mycobacteria Other Than Tuberculosis (MOTT) Infection: A Case Report

Ibrahim Mohamed, Mohamed A Baghi, Vamanjore A Naushad, Basma Ayari, Baraa Mohamed, Qais Al-Said, Ijaz Kamal

Cureus · 2025-11

Abstract

Chronic cavitary pulmonary aspergillosis (CCPA) is a rare, progressive lung infection primarily caused by the Aspergillus species. It typically affects individuals with underlying lung conditions, such as pulmonary tuberculosis (TB), cystic fibrosis, chronic obstructive pulmonary disease (COPD), or interstitial lung disease. Aspergillus fumigatus is the most commonly identified organism. Clinical manifestations can vary from no symptoms at all to chronic cough with or without hemoptysis. Here, we report a 40-year-old male with bilateral CCPA following nontuberculous mycobacterial (NTM) infection, diagnosed after a persistent history of cough, breathlessness, and episodes of hemoptysis.

MeSH terms

  • Medicine
  • Tuberculosis
  • Chronic cough
  • Lung
  • Pulmonary disease
  • Lung disease
  • Nontuberculous mycobacteria
  • Aspergillosis
  • Pulmonary tuberculosis
  • Respiratory disease
  • Interstitial lung disease
  • Disease
  • Internal medicine
  • Pathology
  • History of tuberculosis
  • Productive Cough
  • Lung infection