TB Research

Subcutaneous Migration in Paragonimiasis as a Diagnostic Clue in an Unusual Presentation: A Case Report

Mika Eguchi, Keisuke Masumoto, Mio Tanaka, Haruhiko Maruyama, Satoru Morimoto, Yuichi Mizuta

Cureus · 2025-08

Abstract

. The patient was treated with praziquantel, leading to complete clinical and radiological resolution. This case highlights the diagnostic challenges of paragonimiasis, especially with atypical presentations. Subcutaneous lesions are rare and often mimic benign tumors or other parasitic diseases, such as sparganosis or cysticercosis. The pulmonary findings may be confused with tuberculosis or eosinophilic pneumonia. Thus, thorough dietary and travel history-taking, cultural awareness, and a multidisciplinary diagnostic approach, including imaging, histology, and serology, are essential. Diagnosis of paragonimiasis should rely on a combination of clinical presentation, radiological findings, and serological testing, as ectopic manifestations are uncommon and may not be promptly recognized. This case underscores the need for heightened clinical awareness of re-emerging parasitic diseases in increasingly multicultural societies.

MeSH terms

  • Medicine
  • Paragonimiasis
  • Sparganosis
  • Eosinophilic
  • Paragonimus
  • Eosinophilia
  • Pathology
  • Tuberculosis
  • Serology
  • Abscess
  • Dermatology
  • Helminthiasis
  • Productive Cough
  • Incidence (geometry)