TB Research

Disseminated Extrapulmonary Tuberculosis and Pulmonary Mycobacterium avium Complex Co-infection in a Newly Diagnosed HIV Patient: A Case Report

Priscila Suman Lopez, Wajid Ali, Webster Donaldy, Gurveer Singh Raien, Vel Sivapalan

Cureus · 2025-09

Abstract

complex (MAC) are both serious opportunistic infections (OIs), commonly encountered in immunocompromised individuals, particularly those with HIV. Co-infection with both pathogens is rare but can present significant diagnostic and therapeutic challenges. We report the case of a 45-year-old male who was newly diagnosed with HIV infection and who developed disseminated extrapulmonary TB alongside pulmonary MAC, highlighting the complexities of diagnosis, treatment, and management in the context of dual mycobacterial infections. This case underscores the importance of early recognition and coordinated care in managing multi-pathogen infections in immunocompromised patients.

MeSH terms

  • Medicine
  • Mycobacterium avium complex
  • Human immunodeficiency virus (HIV)
  • Extrapulmonary tuberculosis
  • Tuberculosis
  • Mycobacterium tuberculosis
  • Mycobacterium tuberculosis complex
  • AIDS-Related Opportunistic Infections
  • Coinfection
  • Pulmonary tuberculosis
  • Virology
  • Immunology