TB Research

Tuberculous Infection of a Total Hip Arthroplasty in an Immunocompetent Patient, Revealed by Prosthetic Loosening: A Case Report and Literature Review

Elmostafa Benaissa, S. Oucharqui, Yassine Benlahlou, Adil Maleb, Mariama Chadli, Mostafa Elouennass

Saudi Journal of Pathology and Microbiology · 2025-08

Abstract

Prosthetic joint infection caused by Mycobacterium tuberculosis is extremely rare. It can mimic aseptic loosening or chronic infection with common bacteria, delaying diagnosis. We report a case of tuberculous infection in a total hip arthroplasty in a 55-year-old immunocompetent patient, revealed by prosthetic loosening. The diagnosis was confirmed by histology, culture, and molecular biology (GeneXpert). This case highlights the need to consider tuberculosis in the differential diagnosis of chronic prosthetic infections, particularly in endemic areas.

MeSH terms

  • Total hip arthroplasty
  • Medicine
  • Arthroplasty
  • Prosthesis
  • Surgery
  • Tuberculosis