TB Research

Energy dense nutritional supplements improve weight gain among malnourished adults with drug-sensitive pulmonary tuberculosis: an open-label randomized controlled trial in Faridabad, India

Rakesh Kumar, Pranay Sinha, Anand Krishnan, Manjula Singh, Archna Singh, Randeep Guleria, Urvashi B. Singh

medRxiv · 2025-07

Abstract

This open-label randomized controlled trial in India assessed the impact of a peanut-based energy-dense nutritional supplement (EDNS) on weight gain among undernourished adults with drug-susceptible pulmonary tuberculosis in India. EDNS significantly improved weight gain compared to standard care, offering a scalable solution for targeted nutritional support.

MeSH terms

  • Medicine
  • Randomized controlled trial
  • Open label
  • Weight gain
  • Tuberculosis
  • Malnutrition
  • Drug
  • Pulmonary tuberculosis
  • Environmental health
  • Internal medicine