Rationality of Anti-Tuberculosis Drugs In Adult Pulmonary Tuberculosis Patients at Andalas Public Health Center in Padang

Tuberculosis is a chronic infectious disease caused by the bacteria Mycobacterium tuberculosis. Pulmonary tuberculosis can be cured with appropriate treatment and in accordance with tuberculosis treatment guidelines. Irrationality in the use of antituberculosis drugs, such as inappropriate dosage or inappropriate duration of treatment, can result in resistance, disease recurrence, and serious side effects. This study aims to determine the rationality of using antituberculosis drugs from 5 appropriate aspects (right patient, right indication, right drug, right dose, and right frequency) and to be aware of side effects in adult pulmonary tuberculosis patients at Andalas Public Health Center, in Padang, Indonesia,for the period of January 2025. This research is a type of non-experimental descriptive research. Where data collection was carried out prospectively, using the time limited sampling method. The sample in this study was 31 patients who met the inclusion criteria. Where there were 2 patients who had the wrong dose, namely 1 patient experienced a subdose in the intensive phase and 1 patient experienced a subdose in the advanced phase. The results of evaluating the rationality of using tuberculosis drugs are not 100% rational, because there are still treatments whose accuracy is <100%, namely the right dose with a percentage of 93.54% and 51.59% of patients experiencing drug side effects. Meanwhile, pulmonary TB treatment with 100% accuracy is the right patient, the right indication, the right drug and the right frequency.