TB Research

Do we underestimate pulmonary tuberculosis and coronavirus disease 2019 co-infection? a brief review of a rare case

Radmila Dmitrović, Biljana Lazović, Nevena Jovičić, Isidora Simonović

Egyptian Journal of Chest Diseases and Tuberculosis · 2025-07

Abstract

Introduction Tuberculosis (TB) is the 13th leading cause of death and the second leading infectious disease, following Coronavirus disease 2019 (COVID-19). Co-infection with COVID-19 and tuberculosis has been documented in various parts of the world, and this condition is of interest to many medical professionals. Case report We present a case of COVID-19 and tuberculosis co-infection in a woman with profuse fresh blood vomiting. The COVID-19 polymerase chain reaction (PCR) test yielded a positive. She was initially examined by a gastroenterologist, and pulmonary illness was suspected after further evaluation by an expert ear, nose, and throat (ENT). Computed tomography (CT) of the chest revealed postprimary tuberculosis (PTB). The woman was given antituberculous medications, tranexamic acid, glucocorticoids, low molecular weight heparin (LMWH) in prophylactic doses after the bleeding stopped, and vitamins. Conclusion Co-infection with COVID-19 and tuberculosis is a severe illness, especially in older people with comorbidities, and can lead to disease progression and even death.

MeSH terms

  • Medicine
  • Tuberculosis
  • Coronavirus disease 2019 (COVID-19)
  • Pulmonary tuberculosis
  • Rare disease
  • Disease
  • Coronavirus
  • Intensive care medicine