TB Research

Review 3: "Single-cell Immune Profiling at Time of M. Tuberculosis Exposure Reveals Antigen-Reactive Programs that Predict Progression to Active Disease"

Beth Shoshana Zha

Abstract

Reviewers cautioned on using the term "Mtb-reactive" compared to "Mtb-associated" without providing additional evidence or a nuanced discussion on whether a specific cell state truly recognizes Mtb or is a bystander to another population interacting with it.

MeSH terms

  • Profiling (computer programming)
  • Tuberculosis
  • Antigen
  • Immune system
  • Disease
  • Active tuberculosis
  • Immunology
  • Computational biology
  • Biology