TB Research

Prevalence and risk factor of Mycobacterium tuberculosis among patients attending in upazilla health complex on GeneXpert method at Banskhali Chittagong Bangladesh

Ashish Kumar Shil, Md Shah Alam, Md. Abu Zihad, Helena J. H. van der Pal, Md Obydul Hoq, Md. Iqbal Hossain, Hridoy Chandra Bhoumik, Md. Shohidul Islam, et al. (9 authors)

International Journal of Research in Medical Science · 2025-01

Abstract

Tuberculosis remains a major contributor to illness and death globally. This research was undertaken to assess the prevalence, and associated risk factors of Mycobacterium tuberculosis in individuals suspected of having tuberculosis. A mixed method study design was applied to evaluate the risk factors and prevalence was detected through laboratory testing using the GeneXpert diagnostic method between December 2024 and March 2025. A total of 30 presumptive TB patients were included for quantitative data by face to face interview and 5 service providers and 4 tuberculosis infected patients for qualitative data using indeepth interview. The GeneXpert MTB assay was used to detect the presence of Mycobacterium tuberculosis. Among participants, 50% tested positive for tuberculosis. The average prevalence of tuberculosis infection during the study period was 15% approximately. 33.33% was observed in patients aged over 60 years and above. Risk factor analysis indicated significant associations with smoking (40%) and diabetes (36.67%). The study highlights a notable prevalence of tuberculosis and associated risk factors in the Banskhali region of Chittagong district Bangladesh.

MeSH terms

  • GeneXpert MTB/RIF
  • Tuberculosis
  • Environmental health
  • Mycobacterium tuberculosis
  • Mycobacterium tuberculosis complex
  • Medicine
  • Risk factor