Inactivated mycobacterium paragordonae delivered via microneedle patches as a novel tuberculosis booster vaccine
Moonsu Lee, Dohyeon Jeong, Ki-Young Yoon, Juyoung Jin, Yong Woo Back, In‐Taek Jang, Hwa Jung Kim, Bum‐Joon Kim, et al. (9 authors)
Human Vaccines & Immunotherapeutics · 2025-05
Abstract
delivered via microneedle patches represents an effective booster strategy for enhancing BCG-induced protection against tuberculosis, with a two-dose schedule demonstrating optimal efficacy. This approach combines the safety advantages of an inactivated vaccine with the practical benefits of MAPs, addressing key limitations of tuberculosis vaccination strategies.
MeSH terms
- Mycobacterium tuberculosis
- Tuberculosis
- Tuberculosis vaccines
- Booster (rocketry)
- Virology
- Microbiology
- Medicine
- Booster dose
- Vaccination
- Immunology
- Biology