Skin Prick Test Reactivity to Common Aeroallergens Among the Study Population of 328 Patients

Abstract RATIONALE—Aeroallergens are the predominant triggers of airway inflammation in allergic individuals. Skin prick testing (SPT) is the gold standard for diagnosing causes of allergic conditions. Our study aims to delineate prevalent aeroallergens through standardized SPT procedures. METHODS – A retrospective analysis was performed on a cohort of 328 patients diagnosed with allergic airway disease, all of whom underwent skin prick testing (SPT) from January 2022 to January 2023. The SPT utilized a validated panel comprising 25 allergen extracts alongside 1 positive and 1 negative control. RESULTS – The study encompassed a cohort of 328 patients, among whom 268 individuals (81.70%) tested positive for one or more aeroallergen extracts on SPT. Out of 268 patients, 76, 64 and 128 patients were diagnosed with Allergic Rhinitis, Bronchial Asthma and Allergic Rhinitis with Bronchial Asthma respectively. The highest sensitivity was observed for Dermatophagoides pteronyssinus (141 patients) and Aspergillus Fumigatus (119 patients) amongst dust mites and fungal allergens respectively. (Table 1) CONCLUSION – In our investigation, Mite D pteronyssinus and Aspergillus Fumigatus emerged as the predominant aeroallergens among the study participants. The integration of skin prick testing with a comprehensive patient history stands as a pivotal approach for identifying allergic triggers.