Non-tuberculous mycobacterial lymphadenitis in an infant with Hyper IgM Syndrome: A rare case report

Hyper Immunoglobulin M syndrome is rare. We report a 7-month-old infant who suffered Hyper Immunoglobulin M syndrome and developed non-tuberculous mycobacterial (NTM) lymphadenitis. The former was confirmed by next-generation sequencing revealed X-linked recessive, whilst initial immunoglobulin testing displayed high IgM levels. The latter was diagnosed by lymph node pus acid-fast staining smear, culture and PCR. The child received therapy. Meanwhile, he was treated with immune supporting. The child was followed up for 11 months, and he progressed well.