Reviews of "Spotting the Silent Threat: Early Detection of Subclinical Tuberculosis in High-Risk Individuals"
Hongping Wei, Siti Aishah Rashid, Nurul Farehah Shahrir
Abstract
This preprint presents a multi-center, prospective cohort study evaluating the use of droplet digital PCR (ddPCR) to detect Mycobacterium tuberculosis (Mtb) cell-free DNA in plasma as a tool for early diagnosis of subclinical and incipient TB among high-risk household contacts.The assay demonstrated high sensitivity-up to 90.9% for subclinical TB and 100% for extrapulmonary TB-detecting Mtb DNA as
MeSH terms
- Spotting
- Subclinical infection
- Tuberculosis
- Medicine
- Environmental health