TB Research

Pulmonary amyloidosis: a case report

Fenna Ahsino, Mouad Al Moudni, Jamal Eddine Bourkadi, K. Marc

Oxford Medical Case Reports · 2025-03

Abstract

Amyloidosis is a rare disease in which abnormally folded proteins form accumulations called amyloid fibrils that accumulate in different tissues and organs, sometimes leading to organ dysfunction, organ failure and death. Rarely, pulmonary involvement can take one of three forms: nodular, diffuse alveolar-septal, or tracheobronchial. We report the case of a 60-year-old woman previously treated for confirmed pleural tuberculosis. She was admitted with progressive dyspnea for three months and a chest CT scan revealed a pulmonary nodule in the middle lobe. She underwent CT-guided biopsy and diagnosis of pulmonary amyloidosis was retained by histology. Follow up has been unremarkable.

MeSH terms

  • Medicine
  • Amyloidosis
  • Pathology
  • Biopsy
  • Amyloid (mycology)
  • Pulmonary tuberculosis
  • Histology
  • Nodule (geology)
  • Radiology
  • Tuberculosis