Features of the interpretation of laboratory parameters in tuberculosis: a systematic review

The objective of the study is to conduct a systematic review of the role of molecular genetic methods in the laboratory diagnosis of tuberculosis. The review covers methods such as polymerase chain reaction (PCR), drug resistance detection tests (GeneXpert), and sequencing. The analysis highlights the advantages of these methods compared to traditional diagnostic techniques like microscopy and culture methods. The study also addresses the challenges and prospects of implementing molecular diagnostics in clinical practice. A comprehensive approach was used to gather data from scientific databases (Scopus, Web of Science, MedLine, and others). The main results confirm the high sensitivity and specificity of molecular methods, making them an essential part of modern tuberculosis diagnostics. Conclusions emphasize the need for further integration of molecular technologies with traditional approaches to enhance disease diagnosis and treatment.