A Clinical Case of Generalized Tuberculosis with Lung and Skin Lesions

The article describes a clinical case of generalized tuberculosis with lung and skin lesion in an immunocompetent patient. It was diagnosed based on detection of M. tuberculosis in sputum and wound discharge by microscopy, molecular genetic tests and culture. Genes typical of rifampicin resistance were also found in M. tuberculosis DNA. The following anti-tuberculosis drugs had been used for treatment which was success: Bedaquiline 400 mg, Cycloserine 750 mg, Linezolid 600 mg, Clofazimine 100 mg, and Levofloxacin 1000 mg. In the 9th month of treatment, the patient demonstrated a favorable treatment outcome: conversion was confirmed by sputum and would discharge microscopy. The wounds on the skin of the body and extremities healed.