TB Research

Diffuse pulmonary nodules and diagnostic dilemmas: Lung adenocarcinoma masquerading as miliary tuberculosis

Sonali Mallik, Aparna Behura, Dogga Sri Bharani, Batta Sree Dinesh Kumar

International Journal of Pulmonary and Respiratory Sciences · 2025-01

Abstract

Lung adenocarcinoma is the most common subtype of lung cancer, often presenting with nonspecific symptoms. It is rare for adenocarcinoma to mimic miliary tuberculosis, creating a diagnostic challenge. This case report details a 40-year-old male with a 9-month history of dry cough and shortness of breath. Initial chest X-ray demonstrated a miliary pattern of nodular shadows in both lungs and a homogeneous opacity in the middle zone of the left lung. Contrast-enhanced computed tomography (CECT) of the thorax revealed a mass lesion involving the lingular segment of the left upper lobe and diffuse interstitial coarse reticulations with tiny cysts involving both lung parenchyma. A biopsy taken from the left upper lobe lung lesion confirmed the diagnosis of lung adenocarcinoma.

MeSH terms

  • Medicine
  • Miliary tuberculosis
  • Pulmonary tuberculosis
  • Lung
  • Adenocarcinoma
  • Pathology
  • Tuberculosis
  • Radiology