TB Research

Design, Synthesis and Evaluation of Substituted Benzimidazoles as Potent Polyketide Synthase 13 Inhibitors for Tuberculosis

Gokula Krishnu, Ganesh Paleti, Bharath Kumar Chagaleti, Ahmed Mueen, S Balakrishnan

Journal of Young Pharmacists · 2025-01

Abstract

Gokula Krishnu, Ganesh Paleti, Bharath Kumar Chagaleti, Ahmed Mueen and Shanthakumar Balakrishnan Author informationArticle notesCopyright and License informationCitations Corresponding author. Correspondence: Dr. Shanthakumar Balakrishnan Department of Pharmaceutical Chemistry, SRM College of Pharmacy, SRM Institute of Science and Technology (SRMIST), Kattankulathur, Chengalpattu-603203, Tamil Nadu, INDIA. Email: shanthab@srmist.edu.in July 19, 2024; August 03, 2024; October 06, 2024.

MeSH terms

  • Polyketide synthase
  • Polyketide
  • Tuberculosis
  • ATP synthase
  • Chemistry
  • Stereochemistry
  • Pharmacology
  • Computational biology
  • Medicine
  • Combinatorial chemistry
  • Enzyme
  • Biology