Amplification-free detection of <i>Mycobacterium tuberculosis</i> using CRISPR-Cas12a and graphene field-effect transistors
Weiqi Wang, Hongqiang Du, Changhao Dai, Hongwenjie Ma, Shi Luo, Xuejun Wang, Mingquan Guo, Derong Kong, et al. (9 authors)
Nanoscale · 2025-01
Abstract
M. Cas12a-GFET devices can differentiate 30 positive cases from 56 serum samples within 5 minutes. These findings highlight its immense potential in future biological analysis and clinical diagnosis.
MeSH terms
- CRISPR
- Mycobacterium tuberculosis
- Graphene
- Nanotechnology
- Mycobacterium
- Tuberculosis
- Materials science
- Computational biology
- Microbiology