TB Research

Prevalence and clinical characteristics of individuals presenting with AIDS and late HIV diagnosis in Egypt

Al Sehemy L, Mohamed R, Hatem A, Al-Sharif AM, Awad RA, El Garhy N, Sherif M, Abdelraouf MI, et al. (13 authors)

International journal of STD & AIDS · 2025-11

Abstract

BackgroundEgypt has fastest-growing HIV rate in the Middle East and North Africa. This study aimed to determine the prevalence of late diagnosis (LD) and examine the associated epidemiological and clinical characteristics in a cohort of Egyptian individuals living with HIV.MethodsA cross sectional study included newly diagnosed people living with HIV (PLHIV) who presented to the Cairo University HIV Clinic between September 2022 and May 2023. People with a CD4 + cell count p < 0.05.ResultsOut of 402 newly diagnosed individuals, 65 (16.2%) had LDAD and 172 (42.8%) had LD. The mean age of LD patients was 36.8 ± 10.5 years, and 82.6% were male. The majority (57.4%) had a viral load more than 10,000-100,000 copies/ml. AIDS-related conditions were observed in 52 patients (30.2%), with wasting syndrome (27%), lymphoma (19%), recurrent bacterial infections (19%), and tuberculosis (15%), being the most common..ConclusionThe high prevalence of LD among newly diagnosed PLHIV emphasizes the need for interventions for early HIV testing, and enhancing prevention programs to facilitate early diagnosis and timely initiation of treatment.

MeSH terms

  • Humans
  • HIV Infections
  • Acquired Immunodeficiency Syndrome
  • CD4 Lymphocyte Count
  • Viral Load
  • Prevalence
  • Cross-Sectional Studies
  • Adult
  • Middle Aged
  • Egypt
  • Female
  • Male
  • Delayed Diagnosis