TB Research

Development and validation of a digital health application to support tuberculosis treatment adherence

Andrade-Sales C, Simões-Castro AP, Mendonça-Cavalcante PA, Moreira-Sena MP, Tavares-Cohén GA, Brito-Alves BC, El-Awar UG, Pacheco-Lima KY, et al. (11 authors)

Brazilian journal of biology = Revista brasleira de biologia · 2025-07

Abstract

Tuberculosis remains a serious public health challenge in Brazil, particularly among socially vulnerable populations. This study presents the development and content validation of"Controlling the TB", a digital prototype designed to support treatment adherence among patients undergoing tuberculosis therapy within the Brazilian Unified Health System. The tool was developed based on the Theory of Planned Behavior and User-Centered Design principles, comprising four modules: sociodemographic data, disease history, clinical guidelines, and treatment adherence. Content validation was conducted by expert professionals using a structured instrument and descriptive analysis. All modules met the minimum acceptability criteria, with notable highlights for applicability, accessible language, and clinical coherence. The results demonstrate the prototype's potential as a supportive technology for continuity of care, with national scalability and international adaptability in settings facing similar challenges in treatment adherence and digital monitoring for neglected diseases.

MeSH terms

  • Humans
  • Tuberculosis
  • Reproducibility of Results
  • Telemedicine
  • Adult
  • Middle Aged
  • Brazil
  • Female
  • Male
  • Mobile Applications
  • Treatment Adherence and Compliance
  • Digital Health