Effectiveness of Nursing Care Intervention for Patients With Pulmonary Tuberculosis: A Systematic Review and Meta-Analysis

Aim This review aimed to evaluate the effectiveness of nursing care interventions on various clinical outcomes in patients with pulmonary TB. Design Systematic review and meta-analysis of randomised controlled trials and observational studies. Methods Databases searched included PubMed, Cochrane Library and Web of Science, up to June 2023. Studies were included if they evaluated nursing care interventions for pulmonary TB patients and reported on the specified outcomes. Data were extracted and analysed using a random-effects model, and heterogeneity was assessed using Cochran's Q test and I 2 statistics. Results Sixteen studies were included. Nursing care interventions significantly improved compliance to TB medications (OR = 3.601, 95% CI: 2.366-5.481) and psychological function (SMD = 2.080, 95% CI: 0.502-3.658). Social function and satisfaction also showed significant improvements (SMD = 2.649, 95% CI: 1.496-3.802; OR = 4.943, 95% CI: 2.265-10.786). There was a notable reduction in anxiety (SMD = -2.728, 95% CI: -4.354 to -1.102) and depression (SMD = -1.389, 95% CI: -2.706 to -0.072). Negative sputum conversion rates were higher in the intervention group (OR = 4.943, 95% CI: 2.265-10.786), and the incidence of adverse drug reactions was lower (OR = 0.259, 95% CI: 0.099-0.680). Patient or public contribution No patient or public contribution.