TB Research

Analysis of diagnosis delay among migrant pulmonary tuberculosis patients in Guangzhou from 2014 to 2022

Feng Y, Lai K, Yang J, Lei Y, Wu G, Du Y, He W

Frontiers in public health · 2025-05

Abstract

Background Delays in diagnosing pulmonary tuberculosis (PTB) lead to more severe disease progression and sustained transmission within communities. This study aimed to assess trends and identify risk factors associated with PTB diagnosis delays, especially among migrants, in Guangzhou from 2014 to 2022. Methods Demographic and clinical information of PTB patients from 2014 to 2022 in Guangzhou were extracted from the PTB Information Management System (TBIMS). Diagnosis delays were categorized as patient delay (>30 days from symptoms onset to first care-seeking) and hospital delay (>14 days from first care-seeking to TB diagnosis). Multivariable logistic regression was used to analyze the risk factors for these delays. Results A total of 35,722 migrant PTB patients were registered in Guangzhou during the study period, exhibiting distinct characteristics compared to local residents ( n = 44,155). The bacteriological positivity rate among migrants was significantly lower than that of the local residents (47.68% vs. 52.41%, p Conclusion Public health strategies should prioritize improving bacteriological detection rates among migrants, with targeted efforts for high-risk groups such as females, the older adult, and ethnic minorities.

MeSH terms

  • Humans
  • Tuberculosis, Pulmonary
  • Risk Factors
  • Adolescent
  • Adult
  • Aged
  • Middle Aged
  • Transients and Migrants
  • China
  • Female
  • Male
  • Young Adult
  • Delayed Diagnosis