TB Research

Diagnostic accuracy comparison of the Fluorion MTBC QLP 2.1 real-time PCR and the COBAS TaqMan MTB assays for Mycobacterium tuberculosis detection

Madihi S, Aainouss A, Messaoudi MDE, Benani A

Journal of microbiological methods · 2025-03

Abstract

The Fluorion MTBC QLP 2.1 Real-Time PCR test is a valuable alternative for tuberculosis diagnosis, demonstrating 100 % specificity and 87.5 % sensitivity for respiratory specimens, 97.8 % specificity and 85.3 % sensitivity for non-respiratory specimens, and an overall agreement of 92.3 % with the COBAS TaqMan MTB assay.

MeSH terms

  • Humans
  • Mycobacterium tuberculosis
  • Tuberculosis
  • DNA, Bacterial
  • Molecular Diagnostic Techniques
  • Sensitivity and Specificity
  • Real-Time Polymerase Chain Reaction