TB Research

Reimagining Lupus Vulgaris: Case Studies and Emerging Insights

Rohini Shinde

Journal of Internal Medicine and Pharmacology (JIMP) · 2024-12

Abstract

Tuberculosis remains a significant global health challenge, particularly in developing nations. Lupus vulgaris, a rare and chronic form of cutaneous tuberculosis, poses unique diagnostic difficulties due to its indolent progression and paucibacillary nature. It affects both immunocompromised and immunocompetent individuals, often manifesting in those with prior sensitization to Mycobacterium tuberculosis. This article examines three clinical cases of lupus vulgaris, showcasing its varied presentations and the complexities involved in diagnosis. In addition, a comprehensive review of the literature is presented, covering the epidemiology, pathogenesis, clinical features, diagnostic techniques, and treatment approaches for lupus vulgaris. The aim is to increase awareness and understanding of this under-recognized manifestation of tuberculosis, enabling healthcare professionals to recognize and manage it effectively. Emphasizing the importance of early diagnosis and intervention, this article seeks to improve patient outcomes and address the tuberculosis burden, especially in resource-constrained settings

MeSH terms

  • Lupus vulgaris
  • Systemic lupus erythematosus