Screening of Antimycobacterial Property of Actinobacteria

Tuberculosis (TB) is a pandemic disease caused by Mycobacterium tuberculosis, which infects one-third of the world’s population. The aim of this study was to isolate actinomycetes from samples having antimycobacterial activity for the selected laboratory strains such as Mycobacterium tuberculosis (H37Ra) and Mycobacterium smegmatis. Well diffusion assay and contact bioautography (qualitative assays), microplate alamar blue assay (MABA) and resazurin microtitre assay (REMA) (quantitative assays) were carried out in order to find the inhibition properties of actinomyces extracts.