TB Research

Conditions for extinction and ergodicity of a stochastic Mycobacterium tuberculosis model with Markov switching

Ying He, Bo Bi

AIMS Mathematics · 2024-01

Abstract

<p>This paper is concerned with a stochastic Mycobacterium tuberculosis model, which is perturbed by both white noise and colored noise. First, we prove that the stochastic model has a unique global positive solution. Second, we derive an important condition $ R_0^* $ depending on environmental noise for this stochastic model. We construct an appropriate Lyapunov function, and show that the model possesses a unique ergodic stationary distribution when $ R_0^* < 0 $, in other words, it indicates the long-term persistence of the disease. Finally, we investigate the related conditions of extinction.</p>

MeSH terms

  • Ergodicity
  • Extinction (optical mineralogy)
  • Markov chain
  • Mathematics
  • Statistical physics
  • Mycobacterium tuberculosis
  • Tuberculosis
  • Applied mathematics