Treatment of Latent Tuberculosis Infection in a Kawasaki Disease Patient Receiving Anti-Tumor Necrosis Factor Alpha (TNFα) Therapy
Koji Yokoyama, Toshinari Yakuo, Mitsukazu Mamada
Cureus · 2024-09
Abstract
Kawasaki disease (KD) is a common vasculitis syndrome that mainly affects children. Latent tuberculosis infection (LTBI) is a tuberculosis (TB) infection without signs or symptoms. Here, we report the case of a boy who traveled from abroad, was diagnosed with KD at our hospital, and underwent multidisciplinary treatment, including anti-TNFα therapy. Subsequently, the patient was found to have LTBI and was administered anti-TB treatment. To the best of our knowledge, this is the first reported case of LTBI in a KD patient receiving immunosuppressive therapy containing anti-TNFα.
MeSH terms
- Medicine
- Kawasaki disease
- Latent tuberculosis
- Tumor necrosis factor alpha
- Tuberculosis
- Disease
- Immunology
- Internal medicine
- Mycobacterium tuberculosis