TO STUDY THE DETECTION OF LATENT TUBERCULOSIS IN HIV POSITIVE PATIENTS FROM CHHATTISGARH STATE

Background- The early diagnosis of latent TB infection helpful to patients for better management and treatment of disease. A new approaches to the development of latent TB diagnostics remains a priority of our goals in developing a more sensitive, specic and affordable test that can be applied to the diagnosis of latent TB. ObjectiveThe estimation of CD4, CD8 count of patients, collection of sputum sample of HIV patients, isolation of DNA from sputum sample and PCR based investigation of latent TB infection. Methodology- The study was carried out on 11 subjects with known HIV infection after getting inform consent from the patient. Result- In our study HIV positive patients without TB culture positive, for the detection of latent TB by employing PCR method.