Severe Impairment of T-cell Immunity and Pulmonary GvHD Are Major Risk Factors for Nontuberculous Mycobacterial Infection After Pediatric Allogeneic Hematopoietic Stem Cell Transplantation
Marina Ascunce, Alejandra Coccolo, Yasmina Mozo, Fernando Baquero‐Artigao, Paula Rodríguez-Molino, Carlos Toro, Paloma García-Clemente, Elena Sánchez‐Zapardiel, et al. (15 authors)
The Pediatric Infectious Disease Journal · 2024-05
Abstract
Hematopoietic stem cell transplant recipients are prone to infectious complications. Infections caused by nontuberculous mycobacteria have increased in adults but literature in children is scarce. We report 6 episodes of disseminated or pulmonary nontuberculous mycobacteria infection among 5 pediatric hematopoietic stem cell transplant recipients. All but one were caused by Mycobacterium avium complex. Four patients died, 2 related to nontuberculous mycobacteria infection.
MeSH terms
- Nontuberculous mycobacteria
- Hematopoietic stem cell transplantation
- Medicine
- Stem cell
- Immunology
- Haematopoiesis
- Hematopoietic stem cell
- Transplantation
- Immunity
- Mycobacterium