TB Research

Disseminated mycobacterium genavense infection with central nervous system involvement in an HIV patient: a case report and literature review

Ali Hassanzadeh, Malihe Hasannezhad, Ladan Abbasian, Sara Ghaderkhani, Fereshteh Ameli, Mehdi Allahdadi

BMC Infectious Diseases · 2024-04

Abstract

BACKGROUND: Immunodeficient patients, particularly HIV patients, are at risk of opportunistic infections. Nontuberculous mycobacteria can cause severe complications in immunodeficient patients. CASE PRESENTATION: We describe a 57-year-old HIV patient, primarily presented with coughs and constitutional symptoms, with a unique Mycobacterium genavense abdominal, pulmonary, and central nervous system infection, accompanied by intracranial masses. CONCLUSION: The diagnosis of NTM, including M. genavense, must always be considered by clinicians in immunodeficient patients, especially those with HIV, who have a compromised immune system.

MeSH terms

  • Medicine
  • Medical microbiology
  • Nontuberculous mycobacteria
  • Human immunodeficiency virus (HIV)
  • Presentation (obstetrics)
  • Mycobacterium avium complex
  • Opportunistic infection
  • Immune system
  • Immunology
  • AIDS-Related Opportunistic Infections
  • Central nervous system
  • Intensive care medicine
  • Sida
  • Mycobacterium