TB Research

Injectable isoniazid-loaded bone cement based on hydrazone bonds achieving long-term release and decent mechanical properties

Yang Xu, Hao Lin, Zhe Gao, Rui Guo, Yu-Chen Kan, Lu-yang Han, W. Bu, Zhi Wang, et al. (13 authors)

Journal of Materials Chemistry B · 2024-01

Abstract

studies also indicate that HIA cement exhibits better biocompatibility than INH bone cement. The results of this study not only signify progress in the realm of antimicrobial bone cement for addressing bone tuberculosis but also enhance our capacity to create and comprehend high-performing antimicrobial bone cement.

MeSH terms

  • Bone cement
  • Cement
  • Isoniazid
  • Hydrazone
  • Polymethyl methacrylate
  • Chemistry
  • Biocompatibility
  • Antimicrobial
  • Materials science