TB Research

Newly Identified <i>Mycobacterium africanum</i> Lineage 10, Central Africa

Christophe Guyeux, Gaëtan Senelle, Adrien Le Meur, Philip Supply, Cyril Gaudin, Jody Phelan, Taane G. Clark, Leen Rigouts, et al. (11 authors)

Emerging infectious diseases · 2024-02

Abstract

Analysis of genome sequencing data from >100,000 genomes of Mycobacterium tuberculosis complex using TB-Annotator software revealed a previously unknown lineage, proposed name L10, in central Africa. Phylogenetic reconstruction suggests L10 could represent a missing link in the evolutionary and geographic migration histories of M. africanum.

MeSH terms

  • Lineage (genetic)
  • Phylogenetic tree
  • Biology
  • Phylogenetics
  • Evolutionary biology
  • Mycobacterium tuberculosis
  • Mycobacterium tuberculosis complex
  • Genome
  • Whole genome sequencing
  • Tuberculosis
  • Genetics