TB Research

Role of Vitamin D Level in Tuberculosis Radiology and Laboratory Findings

Kanmaz ZD, Mandal TD, Aras GD

Nigerian journal of clinical practice · 2024-12

Abstract

Background Despite advances in treatment, tuberculosis (TB) remains a significant public health issue. Vitamin D is crucial for the host's immune response against Mycobacterium tuberculosis. Aim This study aimed to investigate the relationship between vitamin D levels and factors determining TB clinical course. Methods We examined 91 patients with TB admitted to Yedikule Chest Diseases Hospital from 2021 to 2022. We investigated the association between vitamin D levels and the prevalence of radiological lesions, duration to sputum and culture conversion, resistance to isoniazid and rifampicin, and patients' age. Results Results showed that 84.60% had low vitamin D levels ( Conclusion In the study, vitamin D levels were consistently low among our patients with TB, and this was particularly associated with widespread radiological lesions. Our study is a real-world investigation highlighting the vitamin D deficiency in TB and underscores the significance of vitamin D in treatment outcomes.

MeSH terms

  • Sputum
  • Humans
  • Mycobacterium tuberculosis
  • Tuberculosis
  • Tuberculosis, Pulmonary
  • Vitamin D Deficiency
  • Isoniazid
  • Rifampin
  • Vitamin D
  • Antitubercular Agents
  • Adult
  • Aged
  • Middle Aged
  • Female
  • Male
  • Young Adult