Role of Vitamin D Level in Tuberculosis Radiology and Laboratory Findings
Kanmaz ZD, Mandal TD, Aras GD
Nigerian journal of clinical practice · 2024-12
Abstract
Background Despite advances in treatment, tuberculosis (TB) remains a significant public health issue. Vitamin D is crucial for the host's immune response against Mycobacterium tuberculosis. Aim This study aimed to investigate the relationship between vitamin D levels and factors determining TB clinical course. Methods We examined 91 patients with TB admitted to Yedikule Chest Diseases Hospital from 2021 to 2022. We investigated the association between vitamin D levels and the prevalence of radiological lesions, duration to sputum and culture conversion, resistance to isoniazid and rifampicin, and patients' age. Results Results showed that 84.60% had low vitamin D levels ( Conclusion In the study, vitamin D levels were consistently low among our patients with TB, and this was particularly associated with widespread radiological lesions. Our study is a real-world investigation highlighting the vitamin D deficiency in TB and underscores the significance of vitamin D in treatment outcomes.
MeSH terms
- Sputum
- Humans
- Mycobacterium tuberculosis
- Tuberculosis
- Tuberculosis, Pulmonary
- Vitamin D Deficiency
- Isoniazid
- Rifampin
- Vitamin D
- Antitubercular Agents
- Adult
- Aged
- Middle Aged
- Female
- Male
- Young Adult