TB Research

Molecular and Serological Detection of <i>Mycobacterium tuberculosis</i> in Dairy Cattle From Sylhet, Bangladesh: Implications for Zoonotic Transmission

Hossain MM, Rahman MM, Rahman MM, Hossain H, Begum R, Chowdhury MSR, Islam MR, Uddin MB

Veterinary medicine international · 2024-10

Abstract

This study aimed to determine the seroprevalence and molecular detection of Mycobacterium tuberculosis ( M. tuberculosis ) in dairy cattle using ELISA and PCR techniques. A total of 500 samples (250 blood and 250 milk) were collected from various farms in Sylhet, Bangladesh. The seroprevalence was found to be 5.6% in blood samples, with PCR confirming 1.60% and 2.80% positivity in blood and milk samples, respectively. These findings highlight the zoonotic potential and public health significance of M. tuberculosis in cattle, suggesting a need for integrated One Health surveillance.