TB Research

Disseminated tuberculosis in PLWHIV presenting as primary adrenal insufficiency

Kumar A, Verma V, Samdarshi S, Muthukrishnan J

BMJ case reports · 2024-05

Abstract

A woman in her 40s presented with a history of fatigue, symptoms of light-headedness on getting up from a sitting position and hyperpigmentation of the skin and mucous membranes. During the evaluation, she was diagnosed with primary adrenal insufficiency. Radiological imaging and microbiological evidence revealed features of disseminated tuberculosis involving the lungs and the adrenals. She was found to have an HIV infection. This patient was prescribed glucocorticoid and mineralocorticoid replacement therapy and was administered antituberculous and antiretroviral treatment.

MeSH terms

  • Humans
  • Tuberculosis, Miliary
  • Tuberculosis, Pulmonary
  • HIV Infections
  • Adrenal Insufficiency
  • Addison Disease
  • Glucocorticoids
  • Antitubercular Agents
  • Diagnosis, Differential
  • Adult
  • Female